Hpv vaccine for oropharyngeal cancer


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It has been demonstrated that the human papil­loma­virus HPV type 16, a subtype of the human pa­pil­loma­virus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive. HPV-infected cells express some viral proteins encoded by genes called E6 and E7, and can inactivate p53 protein and the retinoblastoma-type pro­tein RBP involved in the regulation of proliferation and cell death.

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Implementarea acestuia se bazează pe analizarea frecvenței de apariție a termenului «HPV» în sursele digitalizate tipărite în Engleză între anul și până în prezent. Metastatic HPV-linked head and neck cancer study hpv autoimmune disease According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases.

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Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3].

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In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations in DNA. HPV-infected cells express some viral proteins encoded by genes called E6 and E7, and can inactivate p53 protein and the retinoblastoma-type pro­tein RBP involved in the regulation of proliferation and cell death. Vaccin HPV Materials and method. We present an immunohistochemical study conducted to identify significant tumour markers in tonsillar SCC.

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